Santos Castañeda Selected Research

Giant Cell Arteritis (Horton Disease)

5/2022	Vascular endothelial growth factor haplotypes are associated with severe ischaemic complications in giant cell arteritis regardless of the disease phenotype.
3/2021	Evidence for uncoupling of clinical and 18-FDG activity of PET/CT scan improvement in tocilizumab-treated patients with large-vessel giant cell arteritis.
3/2021	The presence of both HLA-DRB104:01 and HLA-B15:01 increases the susceptibility to cranial and extracranial giant cell arteritis.
1/2021	Tocilizumab in refractory giant cell arteritis. Monotherapy versus combined therapy with conventional immunosuppressive drugs. Observational multicenter study of 134 patients.
10/2020	Cranial and extracranial giant cell arteritis share similar HLA-DRB1 association.
3/2020	Influence of IL17A gene on the pathogenesis of immunoglobulin-A vasculitis.
3/2020	Tocilizumab in giant cell arteritis: differences between the GiACTA trial and a multicentre series of patients from the clinical practice.
1/2019	Tocilizumab in giant cell arteritis. Observational, open-label multicenter study of 134 patients in clinical practice.
1/2018	A TNFSF13B functional variant is not involved in systemic sclerosis and giant cell arteritis susceptibility.
1/2018	Current and emerging diagnosis tools and therapeutics for giant cell arteritis.

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Santos Castañeda Research Topics

Disease

41	Rheumatoid Arthritis 05/2022 - 05/2008
22	Giant Cell Arteritis (Horton Disease) 05/2022 - 07/2009
17	Arthritis (Polyarthritis) 06/2022 - 01/2010
17	Vasculitis (Vasculitides) 05/2022 - 01/2011
12	Interstitial Lung Diseases (Interstitial Lung Disease) 03/2022 - 08/2015
11	Inflammation (Inflammations) 01/2022 - 12/2011
10	Osteoporosis 11/2022 - 01/2008
7	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 06/2012
7	Atherosclerosis 01/2016 - 01/2012
6	Cardiovascular Diseases (Cardiovascular Disease) 05/2019 - 12/2011
6	Purpura 03/2018 - 05/2014
6	Osteoarthritis 07/2013 - 02/2007
5	Systemic Scleroderma (Systemic Sclerosis) 03/2022 - 06/2012
5	COVID-19 01/2022 - 01/2020
5	IgA Vasculitis (Purpura, Schoenlein Henoch) 01/2022 - 01/2015
5	Uveitis 01/2022 - 12/2019
4	Rheumatic Diseases (Rheumatism) 01/2021 - 01/2010
4	Behcet Syndrome (Behcet's Syndrome) 01/2021 - 01/2014
4	Takayasu Arteritis (Arteritis, Takayasu's) 01/2021 - 05/2016
4	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2021 - 05/2008
4	Polymyalgia Rheumatica (Rhizomelic Pseudopolyarthritis) 02/2019 - 06/2012
4	Adult-Onset Still's Disease 01/2019 - 06/2014
3	Obesity 05/2022 - 11/2020
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 05/2022 - 11/2016
3	Axial Spondyloarthritis 01/2022 - 01/2020
3	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2021 - 01/2019
3	Myositis (Idiopathic Inflammatory Myopathies) 01/2021 - 08/2015
3	Psoriatic Arthritis 01/2021 - 11/2014
3	Antisynthetase syndrome 11/2019 - 08/2015
3	Infections 01/2019 - 06/2014
3	Fever (Fevers) 05/2016 - 06/2014
2	Neoplasms (Cancer) 11/2022 - 08/2012
2	Connective Tissue Diseases (Connective Tissue Disease) 03/2022 - 07/2020
2	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022 - 01/2019
2	Dermatomyositis (Dermatopolymyositis) 01/2022 - 07/2020
2	Joint Diseases (Joint Disease) 12/2021 - 01/2011
2	Idiopathic Pulmonary Fibrosis 11/2021 - 08/2021
2	Ankylosing Spondylitis 01/2021 - 01/2021
2	Scleritis (Episcleritis) 01/2020 - 05/2016
2	Necrosis 01/2019 - 01/2018
2	Knee Osteoarthritis 01/2017 - 02/2007
2	Lymphadenopathy 09/2015 - 06/2014
1	Hyperplasia 03/2022
1	Vascular Remodeling 03/2022
1	Proteinuria 03/2022
1	Chronic Kidney Failure (Chronic Renal Failure) 03/2022
1	Lupus Nephritis 03/2022

Drug/Important Bio-Agent (IBA)

14	tocilizumab (atlizumab)FDA Link 01/2022 - 05/2014
11	Biomarkers (Surrogate Marker)IBA 11/2021 - 01/2011
9	Immunoglobulin A (IgA)IBA 01/2022 - 11/2017
8	GlucocorticoidsIBA 01/2022 - 01/2008
7	Anti-Citrullinated Protein AntibodiesIBA 01/2020 - 05/2008
6	Interleukin-6 (Interleukin 6)IBA 03/2022 - 12/2011
6	CytokinesIBA 03/2022 - 01/2018
6	AntibodiesIBA 01/2022 - 01/2013
6	Abatacept (Orencia)FDA Link 12/2021 - 03/2012
6	C-Reactive ProteinIBA 01/2021 - 07/2010
5	AutoantibodiesIBA 01/2022 - 02/2017
5	HLA-B Antigens (HLA-B)IBA 03/2021 - 01/2014
5	Rheumatoid FactorIBA 01/2021 - 01/2017
5	HLA-DRB1 Chains (HLA DRB1)IBA 01/2021 - 01/2015
5	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2021 - 01/2008
4	Ligases (Synthetase)IBA 03/2022 - 11/2019
4	Prednisone (Sone)FDA LinkGeneric 01/2022 - 01/2018
4	Estrogens (Estrogen)FDA Link 07/2013 - 01/2009
3	AdipokinesIBA 05/2022 - 11/2016
3	Biological ProductsIBA 03/2022 - 05/2014
3	Antirheumatic Agents (DMARD)IBA 01/2022 - 07/2013
3	Proteins (Proteins, Gene)FDA Link 01/2021 - 08/2012
3	Interleukin-33IBA 01/2021 - 01/2014
3	InterleukinsIBA 03/2020 - 01/2011
3	Rituximab (Mabthera)FDA Link 09/2019 - 07/2018
3	Glucosamine (Dona)IBA 01/2017 - 02/2007
2	Galectin 1 (LGALS1)IBA 06/2022 - 10/2020
2	AdiponectinIBA 05/2022 - 11/2016
2	Tumor Necrosis Factor InhibitorsIBA 01/2022 - 07/2013
2	N 30IBA 01/2022 - 09/2020
2	Methylprednisolone FDA LinkGeneric 01/2022 - 09/2013
2	Acute-Phase Proteins (Acute-Phase Protein)IBA 01/2022 - 10/2017
2	Diphosphonates (Bisphosphonates)IBA 01/2022 - 01/2016
2	sarilumabIBA 12/2021 - 12/2021
2	Pharmaceutical PreparationsIBA 08/2021 - 06/2015
2	cyclic citrullinated peptideIBA 01/2021 - 01/2013
2	Infliximab (Remicade)FDA Link 01/2021 - 12/2019
2	Lipoproteins (Lipoprotein)IBA 11/2020 - 05/2017
2	Messenger RNA (mRNA)IBA 01/2020 - 04/2015
2	P-SelectinIBA 01/2020 - 01/2017
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 05/2019 - 11/2014
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 12/2018 - 09/2015
2	CSK Tyrosine-Protein KinaseIBA 01/2017 - 10/2015
2	Protein Tyrosine PhosphatasesIBA 01/2017 - 10/2015
2	OsteoprotegerinIBA 11/2016 - 01/2014
2	Interferon Regulatory FactorsIBA 07/2014 - 05/2008
2	Methotrexate (Mexate)FDA LinkGeneric 07/2013 - 03/2012
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 05/2022
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 03/2022

Therapy/Procedure

22	Therapeutics 11/2022 - 06/2014
9	Biological Therapy 01/2021 - 05/2017
2	Ovariectomy (Oophorectomy) 09/2013 - 01/2008
1	Kidney Transplantation 03/2022